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genecards tp53

Complete information for TP53 gene (Protein Coding), Tumor Protein P53, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards – The Human Gene Compendium Acts as a tumor suppressor in many tumor types; induces growth

Symbol Description Category GIFtS GC id Score 1 TP53 Tumor Protein P53 Protein Coding 53 GC17M007661 218.94 2 MDM2 MDM2 Proto-Oncogene Protein Coding 53 GC12P068808 111.97 3 CDKN1A Cyclin Dependent Kinase Inhibitor 1A Protein Coding 50

Symbol Description Category GIFtS GC id Score 1 TP53 Tumor Protein P53 Protein Coding 53 GC17M007661 138.07 2 MDM2 MDM2 Proto-Oncogene Protein Coding 53 GC12P068808 50.61 3 CHEK2 Checkpoint Kinase 2 Protein Coding 53 GC22M028687 40.41 4

11 列 · GeneCards is a searchable, integrative database that provides comprehensive, user-friendly

CATEGORY # OF GENES EXAMPLE GENES
Protein-coding 20,999 PDGFRB PDGFRA FGFR3 FGFR1 RAF1 MET MAP2K1
ncRNA genes 216,457
lncRNAs 72,237 SPATA8 SFTA3 CCDC140 C6orf223 C7orf69 HCP5 C3orf36
pir ncRNAs 109,820 piR-61945-394 piR-61939 piR-61912 piR-61253 piR-61101-485 piR-60

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TP53RK (TP53 Regulating Kinase) is a Protein Coding gene. Diseases associated with TP53RK include Galloway-Mowat Syndrome 4 and Galloway-Mowat Syndrome.Among its related pathways are Gene Expression and tRNA processing..

Complete information for TRIAP1 gene (Protein Coding), TP53 Regulated Inhibitor Of Apoptosis 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards – The Human Gene Compendium UniProtKB/Swiss-Prot

TP73 (Tumor Protein P73) is a Protein Coding gene. Diseases associated with TP73 include Small Cell Cancer Of The Lung and Oligodendroglioma.Among its related pathways are Regulation of TP53 Activity and Direct p53 effectors..

In addition to the full-length protein, the human TP53 gene encodes at least 15 protein isoforms, ranging in size from 3.5 to 43.7 kDa. All these p53 proteins are called the p53 isoforms. [6] The TP53 gene is the most frequently mutated gene (>50%) in humanTP53

Aliases: TP53, BCC7, LFS1, P53, TRP53, tumor protein

GeneCards Summary for TP53 Gene: TP53 (tumor protein p53) is a protein-coding gene. Diseases associated with TP53 include multifocal osteogenic sarcoma, and eyelid neoplasm. GO annotations related to this gene include protein heterodimerization activity .

Complete information for LOC102723655 gene (Protein Coding), TP53-Target Gene 3 Protein, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards – The Human Gene Compendium Free for academic non-profit institutions. Other

TP53 Gene @ GeneCards p53 News provided by insciences organisation David S. Goodsell. RCSB Protein Data Bank. p53 Tumor Suppressor; 2002-07-01 [cited 2008-04-06]. Thierry Soussi. p53 Web Site [cited 2008-04-0 6]. The George Pantziarka TP53 Trust

Regulation of TP53 Activity SuperPath Pathway network for Regulation of TP53 Activity SuperPath 5 Pathways in the Regulation of TP53 Activity SuperPath Regulation of TP53 Activity through Association with Co-factors Transcriptional Regulation by TP53

TP53 tumor protein p53 [] Gene ID: 7157 Summary This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression

点击不同标签可以查询TP53不同方面的信息,命名信息、相关药物、功能、细胞亚定位、不同组织表达量等等信息一应俱全。 简介部分GeneCards也是收录了各个数据库或网站上对该基因的描述,能够帮助我们更加全面地了解这个基因。

GeneCards Suite Affiliated Databases Premium Tools Learn more Set Analyses: Export List GeneALaCart GeneAnalytics VarElect Search Advanced Search Advanced Search Search By Section (entire) for – 4200 GeneCards found for ‘p53’ Sorted by

Complete information for TP53TG3B gene (protein-coding), TP53 target 3B, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards – The Human Gene Compendium Free for academic non-profit institutions. ALL other users need a Commercial license from LifeMap Sciences, Inc.

TP53 Regulates Transcription of Cell Death Genes TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain TP53 Regulates Transcription of Caspase Activators and Caspases

GeneCards is a searchable, integrated, database of human genes that provides concise genomic related information, on all known and predicted human genes About GeneCards®: GeneCards is a searchable, integrated database of human genes that provides comprehensive, updated, and user-friendly information on all known and predicted human genes.

注释内容选项: 注意事项:1.除symbol外至少选择一项注释内容 2.symbol选项不可不选 GeneAlaCart 每节内容 Gene Symbol GeneCards ID GeneCards ID 可选注释项 注释来源 HGNC, NCBI, Ensembl GeneCards, GeneLoc HGNC, UniProt, SwissProt, TrEMBL

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TP53 Regulates Transcription of Cell Cycle Genes SuperPath Pathway network for TP53 Regulates Transcription of Cell Cycle Genes SuperPath

Probability of Dependency: Probabilities of dependency are calculated for each gene score in a cell line as the probability that score arises from the distribution of essential gene scores rather than nonessential gene scores. See here for details.

Complete information for HIPK4 gene (protein-coding), homeodomain interacting protein kinase 4, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards – The Human Gene Compendium Summaries for HIPK4 gene (According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia’s Gene Wiki, PharmGKB,

Complete information for TP53TG1 gene (RNA gene), TP53 target 1 (non-protein coding), including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards

GeneCards TP53 GeneTests TP53 Active transcripts Legend Please note that a short description of a certain column can be displayed when you move your mouse cursor over the column’s header and hold it still. Below, a more detailed description is shown per

The human TP53 gene organization as depicted over the past 20-plus years was simple: it produced a single transcript containing 11 exons encoding a single protein comprising 393 amino acids (Soussi and May 1989). In 1996, Reisman et al. showed that intron 1 of the mouse and human TP53 gene encoded an untranslated transcript whose function is still unknown.

LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to

3/9/2019 · TP53 gene deletion is associated with colorectal carcinomas. IL-13 suppressed both the activation-induced apoptosis of CD4(+) T cells and the expression of p53 and FasL. MDM2 is involved in fibroblast activation, mediating renal tubulointerstitial fibrosis via a

p53遺伝子(ピー53いでんし)とは、一つ一つの細胞内でDNA修復や細胞増殖停止、アポトーシスなどの細胞増殖サイクルの抑制を制御する機能を持ち、細胞ががん化したときアポトーシスを起こさせるとされる。この遺伝子による機能が不全となるとがんが

PDB: オルソログ検索: RCSB PDBe PDBj

Le p53 (ou TP53 pour « tumor protein 53 ») est un facteur de transcription régulant de multiples fonctions cellulaires importantes comme la régulation du cycle cellulaire, l’autophagie ou l’apoptose (mort cellulaire programmée). Chez l’homme, ce gène est situé sur le chromosome 17 [2]..

Masse moléculaire: 43 653 Da

TP53 GeneCards TP53 dbSNP 7157 Diseases TP53 SADR 7157 HugeNav 7157 wikipedia TP53 google TP53 gopubmed TP53 EVS TP53 HEFalMp TP53 MyGene2 TP53 23andMe TP53 UniProt P04637 Ensembl ENSG00000141510 OMIM 191170 # SNPs 262

ClinVar: TP53

TP53 Network SuperPath Pathway network for TP53 Network SuperPath 2 Pathways in the TP53 Network SuperPath TP53 Network Activation, translocation and oligomerization of BAX 20 Genes in the TP53 Network BAX BID ABL1 TP53 TP73 SUMO1 TP63

External References: Wikipedia GeneCards HUGO COSMIC Google Scholar NCBI Description of TP53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein

Summary of TP53 (LFS1, p53) expression in human tissue. Fractions of cells showed weak nuclear and/or cytoplasmic expression. Antibody staining mainly consistent with RNA expression data. Tissue location of RNA and protein might differ due to short half-life of

probably also involved in phosphorylation of 『Ser-392』 of p53/TP53 via its association with CK2 (casein kinase II). Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by

TP53 entry at EntrezGene OMIM review at NCBI TP53 GeneCards entry The p53 pathway at BioSystems p53 target genes and response-elements Gene annotation by Ensembl at EBI p53 entry at Atlas of Genetics p53 protein interactions at Human Protein

LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in Isoform

Gen In menselijke cellen ligt het gen dat voor p53 codeert, TP53 genaamd, op de korte arm van chromosoom 17 (locus 17p13.1). Het gen bestaat uit ongeveer 20.000 nucleotiden (nt), beginnend met een niet-coderend exon en een zeer lang eerste intron van 10.000 nt. Het coderende gedeelte bevat vijf regio’s die sterk geconserveerd zijn onder gewervelde dieren, voornamelijk in exons 2, 5, 6, 7 en 8.

Gen ·

I have list of genes and need to get certain fields of information about them from GeneCards, which is very tedious job manually. Is it possible to access GeneCards via XML so that I can parse it and get the certain fields via script? I am already using xml parsing for

Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

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Accumulation of mutant TP53 if tumoural cells Germinal Germline TP53 mutations are associated with Li-Fraumeni (LFS) and Li-Fraumeni-like syndromes (LFL), characterized by a familial clustering of tumours, with a predominance of soft tissue and bone sarcomas, breast cancers, brain tumours, and adrenocortical carcinomas, diagnosed before the age of 45 years.

p53 es una proteína supresora de tumores.[1] En la especie humana, el gen p53 o TP53, también llamado el 「guardián del genoma」, se encuentra en el brazo corto del cromosoma 17 (17p13) y codifica un factor de transcripción nuclear de 43.7 KDa. Su nombre hace referencia a su masa molecular aparente: corre como una proteína de 53 KDa en un

Especies: Humano, Ratón

Announcement 01/27/2020 Please visit the EDRN Registration page for registration/hotel information for the 35th EDRN Steering Committee Meeting from March 31-April 2, 2020, in Tempe, AZ. Announcement

Direct p53 effectors Singleton SuperPath 1 Pathway in the Direct p53 effectors SuperPath Direct p53 effectors TP53 TP53BP2 TP73 TSC2 TYRP1 VDR BTG2 TRRAP TP63 TNFRSF10D TNFRSF10C TNFRSF10B TNFRSF10A CCNK MAP4K4 GDF15 TP53I3

蛋白质 图片来源:GeneCards 该部分呈现出所有跟「TP53」基因有关的不同的蛋白质,还有不同的蛋白产品、抗体产品等等。 图片来源:GeneCards 图片来源:GeneCards 以抗体产品其中之一为例,点进去看一下这家抗体供应商。

5/8/2010 · GeneCards (www.genecards.org) is a comprehensive, authoritative compendium of annotative information about human genes, widely used for nearly 15 years.Its gene-centric content is automatically mined and integrated from over 80 digital sources, resulting in a

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1. GeneCards 这个发现依赖于谷歌搜索,也依赖于之前学生信的时候遇到的GeneCards。 在谷歌搜索上输入TP53,给我返回的是以下界面,猜测谷歌也会记住我的搜索历史,给我推我最经常访问的网站:维基百科,NIH,NCBI还有GeneCards。